AeroChamber® Plus VHC ゅ膍戈

  • Hodges EGC, Milner AD, Stokes GM, Assessment of a new device for delivering aerosol drugs to asthmatic children. Arch Dis Child 1981; 56:787-800.

  • Toogood JH, Jennings B, Baskerville J, Lefcoe N, Newhouse M. Assessment of a device for reducing oropharyngeal complications during beclomethasone aerosol treatment of asthma. Am Rev Respir Dis 1981; 123(Suppl):113.

  • Corr D, Dolovich M, McCormack D, Ruffin R, Obminski G, Newhouse M. Design and characteristics of a portable breath actuated, particle size selective medical aerosol inhaler. J Aerosol Sci 1982; 13:1-7.

  • Gurwitz G, Levison H, Mindorf C, Reilly P, Worsley G. Assessment of a new device (Aerochamber) for use with aerosol drugs in asthmatic children. Annals of Allergy 1983; 50:166-170.

  • Dolovich M, Ruffin R, Corr D, Newhouse M. Clinical evaluation of a simple demand inhalation MDI aerosol delivery device. Chest 1983;84:36-41.

  • Clinical Evaluation of a simple Demand Inhalation MDI Aerosol Delivery Device ~ Chest 1983;84:p36-41

  • Lawford P, McKenzie D, Alston D. The effect of an aerochamber on bronchodilator response to a metered-dose inhaler. Practitioner 1982;226: 2093-2095.

  • Berenberg MJ, Baigelman W, Cupples LA, Pearce L. Comparison of metered-dose inhaler to an aerochamber with updraft nebulizer for the administration of metaproterenol in hospitalized patients. J Asthma 1985; 22:87-92.

  • Barbera JM, Sly RM, Eby DM, Middleton HB. Responses to a bronchodilator aerosol delivered by Aerochamber to young children. Annals of Allergy 1984;52:224.

  • Newman SP, Moren F, Pavia D, Clarke SW. Deposition studies with spacer devices. In: Metered Dose Inhalers, Epstein SW, ed. Astra Pharmaceuticals Canada Ltd., Mississauga. 1984;107-117.

  • Fractional Deposition From A Jet Nebulizer How It Differs From AMetered Dose Inhaler~Br J Dis Chest 1985;79.63p361-367

    程よ

  • Comparison of Metered-Dose Inhaler Attached to an Aerochamber with an Updraft Nebulizer for the Administration of Metaproterenol in Hospitalized Patients Journal of Asthma-1985;22(2)p87-90

  • Katz R, Rachelefsky G, Rohr A, Wo J, Gracey V, Spector S, Siegel S. Use of tube spacer, Aerochamber(A), to improve the efficacy of a metered dose inhaler (MDI) in asthmatic shildren. J Allergy Clin Immunol 1986;77:185.

  • Fuller H. Comparison of two chamber devices in patients using a metered-dose inhaler with satisfactory technique. CMAJ 1986;135:625-629.

  • A Comparison of Two Delivery Methods for Aerosolized Metaproterenol Sulfate~Joumal of Asthma -1986 ; 23(6) : p297-301

  • MEDICAL INTELLIGENCE CURRENT CONCEPTS CONTROL OF ASTHMA BY AEROSOLS~THE NEW ENGLAND jOURNAL OF mEDICINE -1986p870-873

  • Rachelefsky GS, Rohr AS, Wo J, Gracey V, Spector SL, Siegel SC, Katz RM, Mickey MR. Use of a tube spacer to improve the efficacy of a metered-dose inhaler in asthmatic children. AJDC 1986;140:1191-1193.

  • Head CA, Rogers S, Christopher LE, McNeill CG, George BF, Plummer AL. Comparison of metered dose inhaler with Aerochamber (MDI) and hand held nebulizer (HHN) bronchodilator therapy in hospitalized patients. Am Rev Respir Dis 1987;135:A226.

  • Fairshter RD. Evaluation of a metered-dose aerosol delivery system using partial flow-volume curves. Am Rev Respir Dis 1987;135:741-743.

  • Special report cost-benefit comparison of Aerosol Bronchodilator Delivery Methods in Hospitalized patients~Chest 1987;94(4):p614-618.

  • Crimi N, Palermo F, Cacopardo B, Vancheri C, Oliveri R, Palermo B, Mistretta A. Bronchodilator effec of Aerochamber and Inspirease in comparison with metered dose inhaler. Eur J Respir Dis 1987;71:153-157.

    程よ

  • Salzman GA, Pyszczynski DR. Oropharyngeal candidiasis in patients treated with beclomethasone dipropionate delivered by metered-dose inhaler alone and with Aerochamber. J Allergy Clin Immunol 1988;81:424-8.

  • Equivalence of Continuous Flow Nebulizer and Metered-Dose Inhaler with Reservoir Bag for Treatment of Acute Airflow Obstruction~Chest -1988;p476-481

  • Lee H, Evans HE. Evaluation of inhalation aids of metered dose inhalers in asthmatic children. Chest 1987;91:366-369.

  • Sly RM, Barbera JM, Middleton HB, Eby DM. Delivery of albuterol aerosol by Aerochamber to young children. Annals of Allergy 1988;60:403-406.

  • Gary A. Salzman. MD. and Dennis R. Pyszczynski. MD. FCCP Oropharyngeal candidiasis in patients treated with Beclomethasone dipropionate delivered by metered-dose inhaler alone and with Aerochamber~J Allergy Clin Immunol -J ALLERGY CLIN IMMUNOL 1988;81:p424-428

  • Rothe VT, Mansfeld H-J, Schmitz-Schumann M. Dosieraerosole in der Behandlung des kindlichen Asthma bronchiale. der Kinderarzt 1988;19:679-683.

  • Konig P, Gayer D, Kantak A, Kreutz C, Douglass B, Hordvik NL. A trial of metaproterenol by metered-dose inhaler and two spacers in preschool asthmatics. Pediatr Pulmonol 1988;5:247-51.

  • Aerosol Bronchodilator Delivery Methods~Arch Intern Med -1989

  • Aerosolized Metaproterenol in the Treatment of Asthmatics with Severe Airflow Obstruction~Chest 1989;95:p1017-1020

  • Dexamethasone therapy for chronic lung disease in ventilator-and oxygen-dependent infants Acontrolled frial~JPediatr-1989;115:p979-983

  • Conner WT, Dolovich MB, Frame RA, Newhouse MT. Reliable salbutamol administration in 6- to 36-month-old children by means of a metered dose inhaler and aerochamber with mask. Pediatr Pulmonol 1989;6:263-267.

    程よ

  • Clark AR, Rachelefsky G, Mason PL, Goldenhersh MJ, Hollingworth A. The use of reservoir devices for the simultaneous delivery of two metered-dose aerosols. J Allergy Clin Immunol 1990;85:75-9.

  • Aerosol therapy in the newborn~Archives of Disease in Childhood-1990; p906-908

  • Metered Dose Inhaler Aerosol Characteristics Are Affected by the Endotracheal Tube Actuator Adapter Used~Anesthesiology -1990;73:p1263-1265

  • Benton G, Thomas RC, Nickerson BG, McQuitty JC, Okikawa J. Experience with a metered-dose inhaler with a spacer in the pediatric emergency department. Amer J Dis Child 1989;143:678-81.

  • Lee N, Rachelefsky G, Kobayashi RH, Kobyashi AL, Siegel SC, Katz RM, Spector SL, Rohr AS. Comparison of efficacy and safety of albuterol administered by power-driven nebulizer (PND) versus metered dose inhaler (MDI) with Aerochamber and mask young children with acute asthma. J Allergy Clin Immunol 1991;87:307.

  • Fuller HD, Dolovich MB, Posmituck G, Wong Pack W, Newhouse MT. Pressurized aerosol versus jet aerosol delivery to mechanically ventilated patients: Comparison of dose to the lungs. Am Rev Respir Dis 1990;141:440-444.

  • Salzman GA, Steele MT, Pribble JP, Elenbaas RM, Pyszczynski DR. Aerosolized metaproterenol in the treatment of asthmatics with severe airflow obstruction: Comparison of two delivery methods. Chest 1989;95:1017-20.

  • Aerosol Generators and Delivery Systems~Respiratory Care 1991VOL36 NO 9 p939-951

  • Tesarowski DB, Viel L, Newhouse M, O'Byrne PM, McDonell WN. Equine Heaves as a model for asthma in man. Am Rev Respir Dis 1991;143:A416.

  • How Should Bronchodilators Be Administered to Patients on Ventilators~Respiratory Care 1991;p377-394

    程よ

  • Metered Dose Inhalers for Bronchodilator Delivery in Intubated Mechanically Ventilated Patients~Chest 1991;99:p66-71

  • Effects of Albuterol inhalation on the Work of Breathing during Weaning from Mechanical Ventiltion~Am Rev Respir Dis 1991;144:p95-105

  • Newhouse MT. MDI plus aerochamber: aerosol dosing for controlling reversible airflow obstruction and managing acute exacerbations. Breathing Space 1990;1(3):10-13.

  • Colacone A, Afilalo M, Wolkove N, Kreisman H. A comparison of Albuterol administered by metered dose inhaler (and holding chamber) or wet nebulizer in acute asthma*. Chest 1993;104(3):835-841.

  • Tenholder MF, Bryson MJ, Whitlock WL. A model for conversion from small volume nebulizer to metered dose inhaler aerosol therapy. Chest 1992;101:634-37.

  • clinical investigations Substitution of Metered-dose Inhalers For Hand-Held Nebulizers~Chest p305-308 -19922る

  • Bishop MJ, Larson RP, Buschmann DL. Metered dose inhaler aerosol characertistics are affected by the endotracheal tube actuator/adapter used. Anaesthesiology 1990;73:1263-65.

  • Grigg J, Arnon S, Jones T, Clarke A, Silverman M. Delivery of therapeutic aerosols to intubated babies. Arch Dis Child 1992;67:25-30.

  • A Model for Conversion from Small Vohaler Aerosol Therapy~Chest p634-637 -19923る

  • Everard ML, Clark AR, Milner AD. Drug delivery from holding chambers with attached facemask. Arch Dis Child 1992;67:580-85.

  • An Evaluation of MDI Spacers and Adapters Their Effect on the Respirable Volume of Medication~Respiratory Care 1992;37:p862-868

    程よ

  • Evaluation of a Reservoir Device for Metered-Dose Bronchodilator Delivery to Intubated Adults~CHEST -1992;102:p924-930

  • Rau JL, Harwood RJ, Groff JL. Evaluation of a reservoir device for metered-dose bronchodilator delivery to intubated adults. Chest 1992;102:924-30.

  • Bouchikhi A, Becquemin MH, Roy M, Bertholon JR, Corallo F, Richard E. Etude de la gradulometrie et de la concentration d'un medicament aerosolise (flunisolide). Presented at Congress de Pneumologie de Langue Francaise, Montreal 1991.

  • Campbell R, Dolovich M, Chambers C, Newhouse M. Holding chamber volume/salbutamol dose delivered through an endotracheal tube at low tidal volumes. J Aerosol Med 1992;5:304.

  • Dolovich M, Chambers C, Mazza M, Newhouse MT. Relative efficiency of four metered dose inhaler (MDI) holding chambers (HC) compared to albuterol MDI. J Aerosol Med 1992;5:307.

  • Delivery of Micronized Budesonide Suspension by Metered Dose Inhaler and Jet Nebulizer Into a Neonatal Ventilator Circuit~Pediatr Pulmonol -1992;13:p172-175

  • Delivery of therapeutic aerosols to intubated babies~Archives of Disease in Childhood -1992;67:p25-30

  • Niggemann B. Substitution of metered-dose inhalers for hand-held nebulizers. Chest 1993;103:327.

  • Hofford JM. The metered-dose inhaler supersedes the jet nebulizer. Chest 1993;103:327.

  • Reversibility of exogenous corticosteroid-induced bone loss~Eur Respir -1993,6,p116-119

    程よ

  • Self TH, Kelso TM, Arheart KL., Morgan JH, Meduri GU. Nurses' performance of inhalation technique with metered-dose inhaler plus spacer device. Ann Pharmacother 1993;27:185-7.

  • Nelson HS, Loffert DT. Comparson of the bronchodilator response to metered dose inhaler (MDI) alone or with the Aerochamber (AC) or Optihaler (OP). J Allergy Clin Immunol 1993;91:167.

  • Wolff AH, Oppenheimer J, Bielory L. Comparison of metered dose inhaler (MDI) spacer devices. J Allergy Clin Immunol 1993;91:167

  • Timothy H. Self,Tiffany M. Kelso, Kristopher L. Arheart. Joyce H. Morgan, and G. Umberto Meduri, Nurses Performance of Inhalation Technique With Metered-dose Inhaler Plus Spacer Device~The Annals of Pharmacotherapy Ann Pharmacother-1993;27:p185-187

  • Dosing Efficency and Particle-size Charactristics of Pressurized Metered-dose Inhaler Aerosols in Narrow Catheters~CHEST -1993;103:p920-924

  • Emergency Department Treatment of Severe Asthma~CHEST -1993;103:p665-672

  • Gervais A, Begin P. Bronchodilatation with a metered dose inhaler plus an extension, using tidal breathing vs jet nebulization*. Chest 1987;92(5):822-824.

  • Fink J, Chand R, Jenne JW, Tobin MJ. Effect of simulated patient effort on aerosol deposition during mechanical ventilation: a laboratory bench study. Am Rev Respir Dis 1994;149:A74.

  • Coleman DM, Kelly HW, McWilliams BC, Murphy S. The delivery of aerosolized albuterol through an infant ventilator circuit: comparison of nebulizer and MDI with four spacers. Am Rev Respir Dis 1994;149:A1038.

  • Huang J-L, Hung I-J, Hsieh K-H. Effect of inhaled beclomethasone dipropionate in the treatment of recurrent wheezing in infancy and early childhood. J Formos Med Assoc 1993;92:1066-1069.

    程よ

  • A Comparison of Albuterol Administered by Metered Dose Inhaler (and Holding Chamber )or Wet Nebulizer in Acute Asthma~Chest -1993;104:p835-841

  • Perry BJ, Langenback EG, Ilowite JS. Optimizing aerosol therapy with a new automatic metered dose inhaler/spacer combination. Am J Respir Crit Care Med 1994;149:A217.

  • Cunningham SJ, Crain EF. Reduction of morbidity in asthmatic children given a spacer device. Chest 1994;106:753-57.

  • Campbell SC, Vagedes RT, Yaeger ES. Efficacy of actuator devices in delivery of bronchodilators to mechanically ventilated dogs. Chest 1994;106(Suppl):109S.

  • Sandra J. Cunningham, M. D., Ph.D. Reduction of Morbidity in Asthmatic Children Given a Spacer Device~Chest -Cheat 1994;106:p753-757

  • Perry RJ, Langenback EG, Ilowite JS. Clinical comparison of two aerosol holding chambers: ACE vs Aerochamber. Respir Care 1994;39:1047-1050.

  • Chipps BE, Naumann PF, Wong GA, Raabe OG. Clinical comparison of gentle-haler actuator and aerochamber spacer for metered dose inhaler (MDI) use by asthmatics. Respir Care 1992;37:1414-1422.

  • Facemasks Versus Mouthpieces for Aerosol Treatment of Asthmatic Children -Pediatr Pulmonol-1992;14:p192-196

  • Clarke FE, Montgomery LL, Stubbing D. Randomized comparison of two spacer devices in subjects with reversible airflow limitation. Can Respir J 1994;1:257-60.

    程よ

  • Morris JF, Duncan, CR, Marr ML. Comparison of two techniques for using bronchodilator MDIs plus spacer in COPD. Am J Respir Crit Care Med 1994;149:A310.

  • Henninger D, Tarazewski R, Evans R, Frey C, Albertini R. Comparison of four devices for delivering inhaled bronchodilator in patients with chronic obstructive lung disease (COPD): Patient preference and correlation with spirometry. Am J Respir Crit Care Med 1994;149:A310.

  • Chua HL, Chambers CB, Newhouse MT. Comparison of the effect of four MDI add-on devices on lung deposition and function in asthmatics. Am Rev Respir Dis 1994;149:A217.

  • Dolovich M, Chua HL, Chambers C, lerman J, Newhouse M. A comparison of 8 methods for delivering aerosol to intubated animals. Am J Respir Crit Care Med 1994;149:A1038.

  • Fok TF, Dolovich MB, Newhouse MT, Gray S, Coates G, Monckman S, Paes B, Kirpilani H. Comparison of metered dose inhaler (MDI) and jet nebulizer (JN) in delivery salbutamol (SALB) aerosol to infants with bronchopulmonary dysplasia (BPD). Am J Respir Crit Care Med 1994;149:A546.

  • Bronchodilator aerosol administered by metered dose inhaler and spacer in subacute neonatal respiratory distress syndrome~Archivcs of Disease in Childhood -1994;70:pF218-F222

  • Teper AM, Kofman CD, Maffey AF, Vidaurreta SM, Macri CN, Bergada' I, Heinrich JJ. Effect of inhaled beclomethasone dipropionate (BDP) on pulmonary function, bronchial reactivity and longitudinal growth in infants with bronchial asthma. Am J Respir Crit Care Med 1995;151:A150.

  • Treatment of Bronchospasm by Metered-Dose Inhaler Albuterol in Mechanically Ventilated Patients~Chest 1995;107:p210-213.

  • Bronchodilator Delivery by Metered-dose Inhaler in Ventilator-supported Patients~Am Respir Crit Care Med p1827-1833 -1995;151:p1827-1833

  • Lin Yung-Zen, Hsieh Kue-Hsiung. Metered dose inhaler and nebuliser in acute asthma. Arch Dis Child 1995;72:214-218.

    程よ

  • Parkin PC, Saunders NR, Diamond SA, Winders PM, Macarthur C. Randomised trial spacer v nebuliser for actue asthma. Arch Dis Child 1995;72:239-240.

  • Chou KJ, Cunningham SJ, Crain EF. Metered-dose inhalers with spacers vs nebulizers for pediatric asthma. Arch Pediatr Adolesc Med 1995;149:201-5.

  • Bisgaard H, Anhoj J, Klug B, Berg E. Non-electrostatic-spacer (NES spacer) for aerosol delivery to young children: a comparative study with Nebuhaler, AeroChamber and Babyhaler. J Aerosl Med 1995;8:88(Abstract P97).

  • Ashurst IC, Ambrose CV, Russell DJ. Pharmaceutical evaluation of a new spacer device for delivery of metered-dose inhaler to infants and young children. J Aerosol Sci 1992;23:S499-S502.

  • Manthous CA, Chatila W, Schmidt GA, Hall JB. Treatment of bronchospasm by metered-dose inhaler albuterol in mechanically ventilated patients. Chest 1995;107:210-13.

  • Mitchell J, Nagel M. Comparison of child Aerochamber and Nebuhaler with Budesonide. 10th Biennial Congress, International Society for Aerosols in Medicine. Hamilton, Ontario May 15-19.1995.

  • AARC Clinical Practice Guideline Selection of an Aerosol Device for Neonatal and Pediatric Patients~Respir Care1995;40(12

  • Wu RS-C, Wu KC, Tsai YH, Cheng RK-S, Tan PPC. inhaled fenoterol pretreatment attenuates airway resistance response to endotracheal intubation. Acta Anaesthesiol 1995;33:7-14.

  • Grossman J, Tinkelman DG, Ziment I. Two period multi-dose crossover comparison trial of pirbuterol administered via the Maxair? Autohaler ? with VentolinR via AerochamberR (a spacing device). Abstract-Asthma '95: Theory to Treatment, July 15-17, 1995; Chicago, IL.

  • Dhand R, Jubran A, Tobin MJ. Bronchodilator delivery by metered-dose inhaler in ventilator-supported patients. Amer J Respir Crit Care Med 1995;151:1827-1833.

  • Fok TF, Al-Essa M, Monkman S, Dolovich M, Firard L, Coates G, Kirpalani H. Delivery of metered dose inhaler aerosols to paralysed and non-paralysed ventilated rabbits. Amer J Respir Crit Care Med 1995;151:A746.

  • Chou KJ, Cunningham SJ, Crain EF. Metered-dose inhalers with spacers vs nebulizers for pediatric asthma. Arch Pediatr Adolesc Med 1995;149:201-5.

  • Nair LG, Diamond R, Falcone G, Thakore S, Fine JM. Efficacy of mask spacer with metered dose inhaler in the frail elderly. Chest 1995;108(Suppl):216S.

  • Chua HL, Chambers CB, Newhouse MT. Comparison of MDI and MDI with four add-on devices on lung aerosol deposition and function in asthmatics. J Aerosol Med 1995;8(P82):89.

    程よ

  • Chua HL, Chambers CB, Newhouse MT. Upper respiratory tract(URT) salbutamol (S) Deposition following MDI or MDI+ Aerochamber: Effect of mouth rinsing on oropharyngeal clearance. J Aerosol Med 1995;8(P83):89

  • Ahrens R, Lux C, Bahl T, Han S-H. Choosing the metered-dose inhaler spacer or holding chamber that matches the patient's need: Evidence that the specific drug being delivered is an important consideration. J Allergy Clin Immunol 1995;96:288-94.

  • Shalansky KF, Htan EYH, Lyster DM, Mouat B, Tweeddale MG. In vitro evaluation of the effect of metered-dose inhaler administration technique on aerosolized drug delivery. Pharmacotherapy 1993;13:233-238.

  • Mitchell JP, Nagel MW, Newhouse MT. Comparative performance of small volume plastic-and metal-bodied holding chambers for pediatric use at low tidal volume. Eur Respir J 1996;9(Suppl 23):433S.

  • Albuterol delivery by metered-dose inhaler in a mechanically ventilated pediatric Lung model~Crit Care Med -1996; 24:p870-874

  • Bronchodilator delivery with metered-dose inhalers in mechanically-ventilated Patients~Eur Respir J 1996;9:p585-595

  • Effectiveness of Budesonide Aerosol in Ventilator-Dependnt Preterm Babies A Preliminary Report~Pediatr Pulmonol 1996;21:p231-235

  • Efficiency of Aerosol Medication Delivery From a Metered Dose Inhaler Versus Jet Nebulizer in infants With Bronchopulmonary Dysplasia~Pediatr Pulmonol -1996;21:p301-309

  • TRIAL OF BECLOMETHASONE DIPROPIONATE BY METERED-DOSE INHALER IN VENTILATOR-DEPENDENT NEONATES LESS THAN1500 GRAMS~Am J of Perinatology-1996

  • Determinants of Aerosolized Albuterol Delivery to Mechanically Ventilated Infants~CHHEST -1996;109(6):p1607-1613

  • Mitchell JP, Nagel MW. Comparison of beclomethasone dipropionate(BDP) delivery using a large and small holding chamber-in vitro measurements. Chest 1996;In Press.

  • Childers AG, Cummings RH, Kaufman BD, Glennon JJ, Kelly EL, Lim JC, McNally C. Comparative study of dose delivery and cascade impaction performance of four metered-dose inhaler and spacer combinations. Curr Ther Research 1996;57:75-87

    程よ

  • Clinical investigations Cardiovascular Safety of High Doses of Inhaled Fenoterol and Albuterol in Acute Severe Asthma~Chest -1996;110:p595-603

  • Rau JL, Restrepo RD, Deshpande V. Inhalation of single vs multiple metered-dose bronchodilator actuations from reservoir devices. An in vitro study. Chest 1996;109:969-74.

  • Campbell R, Nantel N, Tseng M, Newhouse M. Larger lung targetable dose of albuterol from HFA MDI than CFC MDI:In vitro measurements. Am J Respir Crit Care Med 1996;153:A63.

  • Tal A, Golan H, Grauer N, Aviram M, Albin D, Quastel MR. Deposition pattern of radiolsbeled salbutamol inhaled from a meterd-dose inhaler by means of a spacer with mask in young children with airway obstruction . pediatr 1996;128:479-84.

  • Dhand R, Tobin MJ. Bronchodilator delivery with metered-dose inhalers in mechanically-ventilated patients. Eur Respir J 1996;9:585-95.

  • Newhouse MT, Chapman KR, McCallum AL, Abboud RT, Bowie DM, Hoder RV, Pare PD, Mesic-Fuch H, Molfino NA. Cardiovascular safety of high doses of inhaled Fenoterol and Albuterol in acute severe asthma . Newhouse MT er al. Chest 1996;110:595-603.

  • Giep T, Raibble P, Zuerlein T, Schwartz ID. Trial of beclomethasone dipropinate by metered-dose inhaler in ventilator-dependent neonates less than 1500 grams. Am J Perinatology 1996;13:5-9.

  • Lee H, Arnon S, Silverman M. Bronchodilator aerosol administered by metered dose inhaler and spacer in subacute neonatal respiratory distress syndrome. Arch Dis Child 1994;70:F218-F222.

  • Arnon S, Grigg J, Silverman M. Effectiveness of budesonide aerosol in ventilator-dependent preterm babies: a preliminary report. Pediatr Pulmonol 1996;21:231-235.

    程よ

  • Gappa M, M. G,, rtner M, K"tting S, Poets CF, von der Hardt H. Effectiveness of aslbutamol by MDI via spacer compared to jet nebulizer on lung mechanics in very preterm infant with lung disease. Eur Respir J 1996;9(Suppl 23):299S.

  • Bisgaard H, Berg E, Madsen J. Dose delivery and fine particle dose of aerosol from three spacers intended for asthma treament in young children. Eur Respir J 1996;9(Suppl 23):431S.

  • Barry PW, O'Callaghan C. The effect of delay on the delivery of fluticasone and salmeterol from spacer devices. Eur Respir J 1996;9(Suppl 23):432S.

  • Barry PW, O'Callaghan C. The effect of breathing pattern on the clearnce of aerosol from spacers. Eur Respir J 1996;9(Suppl 23):432S.

  • Barry PW, O'Callaghan C. The effect of breathing pattern on the output of budesonide from spacers. Eur Respir J 1996;9(Suppl 23):432S.

  • Mitchell JP, Nagel MW. Performance of a 140ml holding chamber with and without opportunity for ambient air ingress during inhalation. Eur Respir J 1996;9(Suppl 23):433S.

  • Mitchell JP, Nagel NW, Dolovich MB. Delivery of beclomethasone dipropionate(BDP) as a function of number of breaths at low tidal volume in two small holding chambers for pediatric use. Eur Respir J 1996;9(Suppl 23):433S.

  • Wildhaber JH, Devadason S, Eber E, Hayden M, Summers QA, LeSou0/00f PN. Electrostatic charge, flow, delay and multiple actuations influence the in vitro delivery of salbutamol from different small volume spacers for infants. Eur Respir J 1996;9(Suppl 23): 433S.

  • Fuller HD, Dolovich M, Newhouse M. The role of spacers in the treatment of mechanically ventilated patients receiving bronchodilators. ISAM Focus Symposium: Aerosol Therapy with Small Volume Nebulizers: Laboratory to Bedside. Tours, France. Sept 4-5, 1996.

  • Newhouse M, Brus RHP, Mahashabde S, Chambers C, Choudhury S, Cooley S. In-vitro comparison of Azmacort_with integral spacer (AZ) vs Aerobid_with Aerochamber_(AB-AC). ACCAI Annual Mtg. Nov 8-13, 1996. Boston, MA.

  • Mitchell JP, Nagel MW, Newhouse MT. Performance of small volume plastic-and metal-bodied holding chambers for pediatric use at low tidal volume. ACCAI Annual Mtg. Nov 8-13, 1996. Boston, MA.

  • Kanter LJ, Kanner RE. Drug delivery from a metered dose inhaler(MDI) used with an inspiratory flow control device(IFCD), compared to a space device(SD). AAAAI 52nd Annual Mtg. March 15-20, 1996. New Orleans, LA.

  • Barry PW, O'Callaghan C. Inhalational drug delivery from seven different spacer devices. Thorax 1996;51:835-840.

  • Vazquez Aceves ML, Gomez Castillo CA, Martinez Cairo S, Cisneros Gonzalez N. Effect of FEV1 induced by the adminstration of salbutamol with aerochamber and metered dose inhaler. [Spanish] Revista Alergia Mexico 1995;42:41-4.

    程よ

  • Bisgaard H, Anhoj J, Klug B, Berg E. A non-electrostatic spacer for aerosol delivery. Arch Dis Child 1995;73:226-30.

  • Amirav I, Goren A, kravitz RM, Pawlowski NA. Physician-targeted program on inhaled therapy for childhood asthma. J Allergy Clin Immunol 1995;95:818-23.

  • Agertoft L, Pedersen S. influence of spacer device on drug delivery to young children with asthma. Arch Dis Child 1994;71:217-9.

  • Arnon S, Grigg J, Nikander K, Silverman M. Delivery of micronized budesonide suspension by metered dose inhaler and jet nebulizer into a neonatal ventilator circuit. Pediatric Pulmonology 1992;13:172-5.

  • Joseph L Rau PhD RRT Ruben D Restrepo MD RRT and Vijay Deshpande MS RRT Inhalation of Single vs Multiple Metered-dose Bronchodilator Actuations From Reservoir Devices~Chest p1996;109-969-74

  • Williams JR, Bothner JP, Swanton RD. Delivery of albuterol in a pediatric emergency department. Pediatr Emerg Care 1996;12:263-267.

  • Mahesh shrestha, MD; Khalil Bidadi, MD; Scott Gourlay, RRT; and James Hayes, MD Continuous vs Intermittent Albuterol at High and Low Doses in the Treatment of Severe Acute Asthma in Adults~Chest 1996;110:p42-47

  • Respiratory Care Standard Abbreviations and Symbols~Respiratory Care-1997 VOL;42NO 6 p637-642

  • Iula Ak, Obetz CL, Deluccia FJ. Compartive study of dose delivery from an Azmacort MDI paired with an Azmacort integrated actuator/spacer, an Aerochamber, Inspirease and a Microspacer. Am J Respir Crit Care Med 1997;155:A672.

  • In vitro comparison of the amount of salbutamol available for inhalation from different formulations used with different spacer devices~Eur Respir 1997;Jp1345-1348

  • Table1 Classification of severity of asthma exacerbation -1997;NIH publication 97-4051

  • Coppolo D, Mitchell JP, Nagel NW. Performance of the MV-Aerochamber holding chamber with CFC-and HFA-formulated albuterol. Am J Respir Crit Care Med 1997;155:A770.

  • Nebuliser therapy in childhood~Tharax -1997;52(supp1 2): s78-s88

  • Nebulisers for asthma~Tharax 1997;52(supp1 2):p s45-s48

  • Ildhaber JH, Hayden MJ, Dore ND, Devadason SG, LeSouef PN. Salbutamol delivery from CFC free pMDI through a plastic spacer in pediatric ventilator circuits. Am J Respir Crit Care Med 1997;155:A671.

    程よ

  • Inhaled Bronchidilator Therapy in Mechanically Ventilated Patients~Am J Respir Crit Care Med pp3-10 -1997

  • Barry PW, O'Callaghan C. The output of salbutamol from spacer devices. Am J Respir Crit Care Med 1997;155:A671.

  • Efficacy of Metered-Dose Inhaler Administration of Albuterol in Intubated~CHEST -1997;112:p484-490

  • Devadason SG, Wildhaber JH, LeSouef PN. The effect of static on the output from large and small spacers used with HFA-inhalers. Am J Respir Crit Care Med 1997;155:A670

  • Wildhaber JH, Devadason SG, Eber E, Hayden MJ, Everard ML, Summers QA, LeSou0/00f PN. Effect of electrostatic charge, flow, delay and multiple actuations on the in vitro delivery of salbutamol from different small volume spacers for infants. Thorax 1996;51:985-988.

  • Wandless JG. Use of the 'Aerochamber' during induction of anaesthesia [letter]. Anaesthesia 1996;51:1193.

  • Raimondi AC, Schottlender J, Lombardi D, Molfino NA. Treatment of acute severe asthma with inhaled albuterol delivered via jet nebulizer, metered dose inhaler with spacer, or dry powder. Chest 1997;112:24-28.

  • Editor's Note:This compilation is adapted from the recommendations of the American Physiological Society and the ACCP-ATS Committee on Pulmonary Nomenclature Some additions have been made Respiratory CARE -JUNE'97VOL42NO6

  • B.J. Lipworth & D.J.Clark Early lung absorption profile of non-CFC salbutamol via small and large volume plastic spacer devices~Br J Clin phormacol 1998; p45-48

  • Salbutamol Delivery From a Hydrofluoroalkane Pressurized Metered-Dose Inhaler in Pediatric Ventilator Circuits~CHEST -1998;113:p186-191

    程よ

  • Eleven peak flow meters a clinical evaluation~Eur Respir J -1998 ;11:p188-193

  • Salbutamol Treatment of Acute Severe Asthma in the ED MDI Versus Hand-Heid Nebulizer~Am J of Emerg-1998; 16: p637-342

  • Hemoptysis Due to MDI Therapy in a Patient With Permsanent Tracheostomy~CHEST 1999;115: p279-282

  • P.W. Barry & C. O'Callaghan A comparative analysis of the particle size output of beclomethasondiproprionate salmeterol xinafoate and fluticasone propionate metered dose inhalers used with the Babyhaler ~Blackwell Science Ltd 1999;47:357-360

  • Optimizing Deposition of Aerosolized Drug in the Lung A Review~www.medscape.com.tw/viewarticle/408738 ~1999

  • MAREK ZAK M.D. JOOP MADSEN M.D. D.M.Sc. and HANS BISGAARD M.D. D.M.Sc A Mathematical Model of Aerosol Holding Chambers~Journal of Aerosol Medicine 1999 Mary ; p187-196

  • AARC Clinical Practice Guideline Selection of Device Administration of Bronchodilator and Evaluation of Response to Therapy in Mechanically Ventilated Patients~Respir Care-1999;44(1):p105-113

  • Reconciling In Vitro and In Vivo Measurements of Aerosol Delivery from aMetered-Dose Inhaler during Mechanical Venttilation and Defining Efficiency-enhancing Factors~Am J Respir Crit Care Med Vol -1999;159:p63-68

  • Hemoptysis Due to MDI therapy in a patient with permanent tracheostomy19991る

  • Evaluating the Delivery of Nebulized-Dose Inhalers in an In Vitro Infant Ventilator Lung Model~Ann Pharmacother -1999;33:p144-148

  • A Comparison of Bronchodilator Therapy Delivered by Nebulization and Metered-Dose Inhaler in Mechanically Ventilated Patients ~CHEST -1999;115 :p1653-1657

    程よ

  • Inhalation therapy in asthma Nebulizer or pressurized metered-dose inhaler with holding chamber in vivo comparison of lung deposition in children 1999:p28~33

  • AeroChamber Plus VHC Gossary -1999

  • Leonard Bielory Frank Picone Paul Rabinowitz Leonard Rossoff John Winder Gary Incaudo Jane Wu and Kenneth Newman Multicentre Randomised Parallel-Group Study of the Efficacy and Tolerability of Flunisolide - Administered Once Daily via AeroChamber in the Treatment of Mild to Moderate Asthma Clin Drug Invest 2000Fed;19(2):93-101

  • Comparison of efficacy and safety between flunisolide AeroChamber and budesonide turbuhaler in patients with moderate asthma~Ann Allergy Asthma Immunol 2000;84:p313-319

  • Costs and effectiveness of spacer versus nebulizer in young children with moderate and severe acute asthma~J Pediatr -2000;136:p497-502

  • Kutay Demirkan PharmD Elizabeth Tollye Mastin RN BSN Judith Soberman MD Joy Burbeck MD and Timothy Self PharmD. Salmeterol Administration by Metered-Dose Inhaler Alone vs Metered-Dose Inhaler Plus Valved Holding Chamber - CHEST 2000; 117:1314-1318

  • Variability in lung deposition inhaled drug,within and between asthatic patients,with a pMDIand dry powder inhaler,turbuhaler~International Journal of Pharmaceutics-1999;193(2000):p227-230

  • Nebulizers Principles and Performance~Respiratory Care 2000;45(6): p609-622

  • Leonard Bielory Frank Picone Paul Rabinowitz Leonard Rossoff John Winder Gary Incaudo Jane Wu and Kenneth Newman Multicentre Randomised Parallel-Group Study of the efficacy and Tolerability of Flunisolide Administered Once Daily via AeroChamber in the treatment of Mild to Moderate Asthma 2000Fed:19 (2):93-101

    程よ

  • Salmeterol Administration by metered Dose Inhaler Alone vs Metered-Dose Inhaler Plus Valved Holding Chamber ~Chest -2000May;117:91314-1318

  • H J Zar, E G Weinberg, H J Binns, F Gallie M D Mann Lung deposition of aerosol-a comparison of different spacers~Arch Dis Child 2000;82:495-498

  • Consensus Statement Aerosols and Delivery Devices~Respiratory Care -2000;45(6): p589-596

  • Aerosol Device Selection Evidence to Practice~Respiratory Care -2000;45(7):p874-885

  • Water accumulation in metered dose inhaler spacers under normal mechanical ventilation conditions~Heart&Lung 2000;29:424-428.

  • Inhaled Fraction~Article received DIOT ET AL. 2000;p58-64

  • Budesonide Inhalation Suspension A Review of its Use in Infants Children and Adults with Inflammatory Respiratory Disorders~Drugs2000 11;60

  • Successful implementation of spacer treatment guideline for acute asthma2001;84:p142-146

  • FEV1 Useful in Assessing Airway Responsiveness in Asthmatic Children~Chest 2001;120:1843-1849

  • Oxygen Should Be First Treatment Given to Patients With Severe Asthma~BMJ 2001;323:p98-100

  • C V E Powell, G R Maskell, M K Marks, M South, C F Robertson. Successful implementation of spacer treatment guideline for acute asthma~Arch Dis Child -2001;84:p142-146

  • ARIEL BERLINSKI M.D. and J. CLIFFORD WALDREP Ph.D. Metering Performance of Several Metered-Dose Inhalers with Different Spacers Holding Chambers~Journal of Aerosol Medicine 2001 Mary;p427-432 -

  • The Equivalence of Compressor Pressure-Flow Relationships with Respect to Jet Nebulizer Aerosolization Characteristics~Journal of Aerosol Medicine -2001p31-42

  • E Dompeling A M Oudesluys-Murphy h m Janssens H M Janssens W Hop J G Brinkman R N Sukhai J C de Jongste Randomised controlled study of clinical efficacy of spacer therapy in asthma with regard to electrostatic charge~Arch Dis Child 2001;84:p178-182

  • JACKIE RICHARDS PhD PETER HIRST PhD GARY PITCAIRN PhD SHASHANK MAHASHABDE PhD WATTANAPORN ABRAMOWITZ PhD ARNO NOLTING PhD and STEPHEN P NEWMAN PhD Deposition and Pharmacokinetcs of Flunisolide Delivered from Pressurized Inhalers Containing Non-CFC Propellants -JOURNAL OF AEROSOL MEDICINE -2001Mary;p197-208

    程よ

  • Component1~Gpldcopd exec summary 2001

  • Component3 Manage Siable COPD~Goldcopd exec summary 2001

  • Component4 Manage Exacerbations ~Goldcopd exec summary 2001

  • N. M. Eiser C. Phillips AND P. A. WOOLER Does the mode of inhalation affect the bronchodilator response in patients with severe COPD~Restpiratory Medicine -(2001)95, p476-483

  • Aerosol Therapy With Valved Holding Chambers in Young Children Importance of the Facemaskseal~Pediatrics-2001;p389~394

  • Management of Acute Exacerbations of Chronic Obstructive Pulmonary Disease~Pharmacotherapy 2001;21(8)p929-939

  • Effective Dose of Salmeterol Can Be Administered With Valved Holding Chamber~Ann Allergy Asthma Immunol -Ann Allergy Asthma Immunol 2001;87:482-487

  • Israel Amirav MD and Michael T Newhouse MD MSc FRCP(C) FACP FCCP Aerosol Therapy With Valved Holding Chambers in Young Children Importance of the Facemask Seal -PEDIATRICS Vol.108 NO 2 AUGUST 2001

  • Michael J. Asmus PharmD Judy Liang PharmD Intira Coowanitwong MS Ramin Vafadari and Guenther Hochhaus PhD In vitro deposition of fluticasone aerosol from ametered inhaler with and without two common valved holding chambers~Ann Allergy Asthma Immunol 2002;88:152-161

  • Global strategt for asthmama management and prevention -2002

    程よ

  • Optimizing Deposition of Aerosolized Drug in the Lung A Review -2002

  • Fluticasone Inhaler Use May Cause Laryngitis~Ach Otolaryngol Head Neck Surg -2002;128:p677-681

  • Asmus MJ Liang J,Coowanitwong I, Vafadari R,Hochhaus G. In vitro deposition of Fluticasone aerosol from a metered-dose inhaler with and without two common valved holding chambers~Ann Allergy Asthma Immunol -2002 Fed;88(2):p204-208

  • Performance of large-and small-volume valved holding chambers with a new combination long-term bronchodilator anti-inflammatory formulation delivered by pressurized metered dose inhaler~J Aerosol 2002Med ;15(4):427-33

  • Nebulizers vs Metered-Dose Inhalers With Spacers for Bronchodilator Therapy to Treat Wheezing in Children Aged 2 to 24 Months in a Ped0iatric Emergency Department 2003;157:p76-80

  • An in vitro investigation of common nebulizer dosing protocols comparing a breath-actuated with conventional pneumatic small volume nebulizer~Respiratory Drug Delivery 2003;48(1):p46-51

  • Current Concepts in Pharmacologic Management of Chronic Obstructive Pulmonary Disease~www.medscape.com viewarticie 417589 www.medscape.com -2003

  • Inhaled glucocorticoids versus leukotriene receptor antagonists as single agent asthma treatment systematic review of current evidence -2003;326:p621-3

  • Effect of montelukast added to inhaled budesonide on control of mild to moderate asthma~Tharax -2003;58:p204-211

    程よ

  • Effect of the Addition of Montelukast to Inhaled Fluticasone Propionate on Airway Inflammation~Am J Respir Crit Care Med -2003;167:p745-750

  • Lung Deposition and Respirable Mass During Wet Nebulization~Journal Of Aerosol Medicine -2003;pp379-386

  • Albuterol Aerosol Delivered vie Metered-Dose Inhaler to Intubated Pediatric Models of 3Ages With 4Spacer Designs~Respiratory Carep-2003;948-955

  • The Delivery of ChloroFluorocarbon-Propelled Versus Hydrofluoroalkane-Propelled Patient A Laboratiory Study~Respiratory Care 2003;pp1025-1032

  • Safety of inhaled corticosteroids delivered by plastic and metal spacers~Arch Dis Child 2003527~528

  • Accuracy of Float Testing for Metered-Dose Inhaler Canisters ~www.medscape.com viewarticle 449883 print -2003

  • Use of the AeroChamber Brand of Valved Holding Chamber in the ER~Printed in Canada MD-2003;157:76-80.

    程よ

  • The Delivery of ChloroFluorocarbon-Propelled Versus Hydrofluoroalkane-Propelled Patient A Laboratiory Study~Respiratory Care -2003;pp1025-1032

  • Comparison of Breath-actuated and Conventional Constant-Flow Jet Nebulizers in Treating Acute Asthmatic Children~Acta PaediatrTw 2004 ;45: 73-6

  • Performance Comparison of Nebulizer Design Constant-output Breath-Enhanced and Dosimetric2004;49(2):p174-179.

  • ˙币笆籔尿瑈蔼溃砰铭て竟ノ獀励齿眞担ぇゑ耕~狶莱礛20044る

  • The influence of formulation and spacer device in vitro performance of solution chorofluorocarbon-free propellant-driven metered dose inhalers~Controlled Clinical Trials 2004;pp286-310

  • 2004The Inhalation of Drugs Advantages and Problems~ Respir Care 2005;50(3):p367-382.

  • 2004 Philip Kittredge Memorial Lecture The Inhalation of Drugs Advantages and Problems -Respir Care 2005-50-3-p367-382

  • 芖洛厩Formosan Journal of Medicine 2005;9:18-28.

    程よ